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Bangladesh COVID-19 vaccination coverage factors older adults

Published On: 18 February, 2022

Published On: 27 January, 2022

Published On: 15 November, 2022

Published On: 17 October, 2022

COVID-19 coping strategies nurses pandemic patient care scoping review

Published On: 28 April, 2022

Bangladesh COVID-19 CRP dyspnea lymphopenia makeshift hospital older age

Published On: 10 June, 2022

COVID-19 Sarcoidosis Protein-protein interaction Hub genes Drug network Vitamin D

Published On: 07 February, 2022

CAPA COVID-19 Fungal coinfection IPA Mucormycosis SARS-CoV-2

Published On: 09 May, 2022

Published On: 04 November, 2022

Published On: 23 August, 2022

ACE1 ACE2 COVID-19 SARS-CoV-2 meta-analysis

Published On: 23 September, 2022

Published On: 18 August, 2022

Bangladesh COVID-19 antimicrobial resistance antimicrobial stewardships community engagement consumption behavior

Published On: 04 February, 2022

Belief Rule Base COVID-19 Transfer Learning VGG Net Validation Accuracy

Published On: 21 December, 2021

Published On: 15 August, 2022

Published On: 01 September, 2022

COVID-19 Health personnel Mental health Nurses Pandemics Psychological adaptation

Published On: 14 March, 2022

Published On: 04 April, 2022

Published On: 02 June, 2022

Bangladesh COVID-19 anthropology cultural explanatory model health illness and disease rapid ethnographic assessment

Published On: 11 May, 2022

Envelope protein Epitope-based vaccine Immunoinformatics Membrane glycoprotein SARS-CoV-2 Spike surface glycoprotein Immunogenic Neutralizing antibody

Published On: 25 May, 2022

Adverse effects COVID-19 vaccines Distribution Effectiveness Immunogenicity SARS-CoV-2

Published On: 07 February, 2022

Bangladesh COVID-19 SARS-CoV-2 central control room integrated approach prevention and therapy

Published On: 13 September, 2022

depression COVID-19 severe acute respiratory syndrome coronavirus 2 recovery Bangladesh sleep-wake disorders

Published On: 05 February, 2021

COVID-19 Depression Anxiety Stress Insomnia Meta-analysis Health professionals

Published On: 07 July, 2021

coronavirus e‐health health policy health care service telehealth

Published On: 28 August, 2020

SARS-CoV-2 Prevaccination IgG Antibody

Published On: 27 January, 2022

Socialization School closure Coronavirus Bangladesh Urban

Published On: 10 November, 2021

COVID-19 psychological impact Insomnia Sleep problems Fear of COVID-19 GIS-Based nationwide study Bangladesh

Published On: 26 April, 2021

COVID-19 Asthma Respiratory distress Pathophysiology Medications Self-care Telehealth Risk Management

Published On: 05 February, 2022

Infection vaccination COVID-19 healthcare professional academic platform

Published On: 18 February, 2022

Gender differences COVID-19 adults Bangladesh

Published On: 12 January, 2022

SARS-CoV-2 Sequence Phylogeny Variant Mutation Bangladesh

Published On: 22 October, 2021

COVID‐19 Bangladesh

Published On: 26 January, 2022

COVID-19 Health care workers Personal protective equipment infection prevention control Bangladesh

Published On: 21 October, 2021

COVID-19 comorbidity medicinal plants Artemisia herba-alba molecular docking

Published On: 13 January, 2022

COVID-19 antimicrobial resistance consumption behavior antimicrobial stewardships community engagement Bangladesh

Published On: 28 January, 2022

SARS-CoV-2 COVID-19 pandemic Second wave Vaccines SARS-CoV-2 variants Host immunity Non- pharmaceutical interventions

Published On: 16 February, 2022

COVID-19 psychological impact depression anxiety internet use behaviors Bangladeshi students

Published On: 01 September, 2020

medical students depressive symptoms patient health questionnaire-(PHQ-9) COVID-19 Bangladesh

Published On: 31 January, 2022

SARS-CoV-2 COVID-19 neonates low- and middle-income country Bangladesh

Published On: 12 December, 2020

Mutation SARS-CoV-2 Molecular phylogeny Protein structure Frequency Bangladesh

Published On: 12 July, 2021

COVID-19 vaccine lifestyle attitude behavior post-vaccination

Published On: 21 January, 2022

Travel mode Risk perception COVID-19 Psychology Modal shift

Published On: 20 January, 2022

chemokines COVID‐19 cytokines disease severity proinflammatory molecules relative expression
Aggressive immune response, due to overexpressed proinflammatory molecules, has been characterized in coronavirus disease 2019 (COVID‐19) patients. Some of those mediators have a dual and opposite role on immune systems at play behind dif- ferential disease severities. We investigated the expression of some cytokines and chemokines in COVID‐19 patients in Bangladesh. We diagnosed the patients by detecting severe acute respiratory syndrome coronavirus 2 RNA in nasal swab samples by the real‐time RT‐PCR method. Thirty adult patients were preselected based on their disease severities and grouped into mild, moderate, and severe cases. Nine healthy volunteers participated in this study as a control. Relative expression of nine cytokines/chemokine in total leukocytes was semi‐quantified in SYBRgreen‐ based real‐time quantitative reverse‐transcriptase polymerase chain reaction. We performed statistical tests on transformed log data using SPSS 24.0. At the onset of symptoms (Day 1), angiotensin‐converting enzyme 2 (ACE2) (p < 0.05) and inter- leukin (IL)‐6 (p > 0.05) were upregulated in all COVID‐19 groups, although the ex- pression levels did not significantly correlate with disease severities. However, expressions of IL‐6, monocyte chemotactic protein‐1, macrophage inflammatory protein‐1α, tumor necrosis factor‐α (TNF‐α), RANTES (regulated upon activation, normal T cell expressed and secreted), and ACE2, on Day 14, were positively cor- related with disease severities. Relative viral load at Day 1 showed no significant correlation with cytokine expression but had a significant positive correlation with RANTES and ACE2 expression on Day 14 (p < 0.05). Male patients had a higher level of IL‐6 than female patients on Day 1 (p < 0.05). All COVID‐19 patients showed upregulated cytokines and chemokines on Day 14 compared to Day 1 except TNF‐α. Female patients had a higher expression of ACE2 and IL‐12 on Day 14. Upregulated cytokines/chemokines at the convalescent stage, especially IL‐6, may help in tar- geting anticytokine therapy in post‐COVID‐19 patients' management.

Published On: 29 May, 2021

Depression Anxiety Mental health COVID-19 Outbreak

Published On: 15 June, 2021